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CHEBI:229948 - N,N,N-Trimethyl-L-alanyl-L-proline betaine (TMAP)

ChEBI IDCHEBI:229948
ChEBI NameN,N,N-Trimethyl-L-alanyl-L-proline betaine (TMAP)
Stars
Definitionbelongs to the class of organic compounds known as dipeptides. TMAP was previously an unknown potential plasma biomarker for glomerular filtration rate (GFR) but its structure has since been elucidated (PMID: 28706470 ). TMAP has also been identified as a potential plasma biomarker of reduced kidney function in early chronic kidney disease (CKD), end stage renal disease (ESRD), and hemodialytic clearance (PMID: 31048706 )
Submitterntejera
DownloadsMolfile
FormulaC11H20N2O3
Net Charge0
Average Mass228.292
Monoisotopic Mass228.14739
SMILESC[C@@H](C(=O)N1CCC[C@H]1C(=O)[O-])[N+](C)(C)C
InChIInChI=1S/C11H20N2O3/c1-8(13(2,3)4)10(14)12-7-5-6-9(12)11(15)16/h8-9H,5-7H2,1-4H3/t8-,9-/m0/s1
InChIKeyKXONJPJIFNGMCN-IUCAKERBSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - MetaboLights (MTBLS9394)
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
ChEBI Ontology
Outgoing Relation(s)
N,N,N-Trimethyl-L-alanyl-L-proline betaine (TMAP) (CHEBI:229948) is a dipeptide (CHEBI:46761)
IUPAC Name 
(2S)-1-[(2S)-2-(trimethylazaniumyl)propanoyl]pyrrolidine-2-carboxylate
Manual XrefsDatabases
HMDB0240365HMDB
Citations