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CHEBI:229646 - gepirone hydrochloride

Default Structure
ChEBI IDCHEBI:229646
ChEBI Namegepirone hydrochloride
Stars
DefinitionThe hydrochloride salt of gepirone. It is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder.
Last Modified19 February 2024
SubmitterAdnan
DownloadsMolfile
FormulaC19H29N5O2.HCl
Net Charge0
Average Mass395.935
Monoisotopic Mass395.20880
SMILESCC1(C)CC(=O)N(CCCCN2CCN(c3ncccn3)CC2)C(=O)C1.Cl
InChIInChI=1S/C19H29N5O2.ClH/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18;/h5-7H,3-4,8-15H2,1-2H3;1H
InChIKeyDGOCVISYYYQFEP-UHFFFAOYSA-N
Roles Classification
Biological Role:
serotonergic agonist  An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
Applications:
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
serotonergic agonist  An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
ChEBI Ontology
Outgoing Relation(s)
gepirone hydrochloride (CHEBI:229646) has part gepirone(1+) (CHEBI:229647)
gepirone hydrochloride (CHEBI:229646) has role antidepressant (CHEBI:35469)
gepirone hydrochloride (CHEBI:229646) has role anxiolytic drug (CHEBI:35474)
gepirone hydrochloride (CHEBI:229646) has role serotonergic agonist (CHEBI:35941)
gepirone hydrochloride (CHEBI:229646) is a hydrochloride (CHEBI:36807)
IUPAC Name 
4,4-dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione hydrochloride
Synonyms  Source
1-[4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)butyl]-4-(pyrimidin-2-yl)piperazin-1-ium chlorideIUPAC
4,4-dimethyl-1-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}piperidine-2,6-dione—hydrogen chlorideIUPAC
BMY 13805ChEBI
BMY-13805ChEBI
BMY 13805-1ChEBI
gepirone ERChEBI
Brand Name  Source
ExxuaKEGG DRUG
Manual XrefsDatabases
D04314KEGG DRUG
DBSALT002148DrugBank
EP1343504Patent
Registry NumbersSources
CAS:83928-66-9DrugBank
Citations