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CHEBI:228678 - Temazepam-d5

ChEBI IDCHEBI:228678
ChEBI NameTemazepam-d5
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC16H8ClD5N2O2
Net Charge0
Average Mass305.776
Monoisotopic Mass305.09794
SMILES[2H]c1c([2H])c([2H])c(C2=NC(O)C(=O)N(C)c3ccc(Cl)cc32)c([2H])c1[2H]
InChIInChI=1S/C16H13ClN2O2/c1-19-13-8-7-11(17)9-12(13)14(18-15(20)16(19)21)10-5-3-2-4-6-10/h2-9,15,20H,1H3/i2D,3D,4D,5D,6D
InChIKeySEQDDYPDSLOBDC-VIQYUKPQSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) urine (BTO:0001419) MetaboLights (MTBLS8662)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Temazepam-d5 (CHEBI:228678) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
7-chloro-3-hydroxy-1-methyl-5-(2,3,4,5,6-pentadeuteriophenyl)-3H-1,4-benzodiazepin-2-one
Manual XrefsDatabases
27523923ChemSpider