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CHEBI:228289 - pachyaximine A
| Formula | C24H41NO |
| Net Charge | 0 |
| Average Mass | 359.598 |
| Monoisotopic Mass | 359.31881 |
| SMILES | [H][C@@]12CC=C3C[C@@H](OC)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@H](C)N(C)C |
| InChI | InChI=1S/C24H41NO/c1-16(25(4)5)20-9-10-21-19-8-7-17-15-18(26-6)11-13-23(17,2)22(19)12-14-24(20,21)3/h7,16,18-22H,8-15H2,1-6H3/t16-,18-,19-,20+,21-,22-,23-,24+/m0/s1 |
| InChIKey | ZTNBSFMIFOLVCM-MCTVSQGJSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Sarcococca saligna (ncbitaxon:153583) | whole plant (BTO:0001461) | PubMed (15795993) | |
| Sarcococca hookeriana (ncbitaxon:153579) | Root (BTO:0001188) | PubMed (29762510) | |
| Pachysandra procumbens (ncbitaxon:83909) | - | PubMed (9784163) |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | EC 3.1.1.7 (acetylcholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. EC 3.1.1.8 (cholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| Applications: | hepatoprotective agent Any compound that is able to prevent damage to the liver. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| pachyaximine A (CHEBI:228289) has role antibacterial agent (CHEBI:33282) |
| pachyaximine A (CHEBI:228289) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462) |
| pachyaximine A (CHEBI:228289) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733) |
| pachyaximine A (CHEBI:228289) has role hepatoprotective agent (CHEBI:62868) |
| pachyaximine A (CHEBI:228289) has role immunosuppressive agent (CHEBI:35705) |
| pachyaximine A (CHEBI:228289) has role plant metabolite (CHEBI:76924) |
| pachyaximine A (CHEBI:228289) is a aza-steroid (CHEBI:35726) |
| pachyaximine A (CHEBI:228289) is a steroid alkaloid (CHEBI:26767) |
| pachyaximine A (CHEBI:228289) is a tertiary amino compound (CHEBI:50996) |
| IUPAC Name |
|---|
| (20S)-3β-methoxy-N,N-dimethylpregn-5-en-20-amine |
| Synonyms | Source |
|---|---|
| alkaloid-C | ChEBI |
| pachyaximine-A | ChEBI |
| (−)-pachyaximine A | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| C00028789 | KNApSAcK |
| Registry Numbers | Sources |
|---|---|
| CAS:128255-08-3 | ChEBI |
| Citations |
|---|