CHEBI:22719 - benzodiazepine alkaloid

ChEBI IDCHEBI:22719
ChEBI Namebenzodiazepine alkaloid
Stars
DefinitionAny alkaloid based on a benzodiazepine skeleton and its substituted derivatives.
Last Modified17 April 2015
Roles Classification
Biological Roles:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
benzodiazepine alkaloid (CHEBI:22719) is a alkaloid (CHEBI:22315)
benzodiazepine alkaloid (CHEBI:22719) is a benzodiazepine (CHEBI:22720)
Synonym  Source
benzodiazepine alkaloidsChEBI