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CHEBI:223248 - Prothracarcin

ChEBI IDCHEBI:223248
ChEBI NameProthracarcin
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC14H14N2O
Net Charge0
Average Mass226.279
Monoisotopic Mass226.11061
SMILESC/C=C1\C[C@H]2C=Nc3ccccc3C(=O)N2C1
InChIInChI=1S/C14H14N2O/c1-2-10-7-11-8-15-13-6-4-3-5-12(13)14(17)16(11)9-10/h2-6,8,11H,7,9H2,1H3/b10-2+/t11-/m0/s1
InChIKeyGYUDGZRJHSDPLH-KJQCOJPZSA-N
Species of MetaboliteComponentSourceComments
Streptomyces (ncbitaxon:1883) - PubMed (7142014)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Prothracarcin (CHEBI:223248) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(6aS,8E)-8-ethylidene-7,9-dihydro-6aH-pyrrolo[2,1-c][1,4]benzodiazepin-11-one
Manual XrefsDatabases
10298950ChemSpider