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CHEBI:221260 - Limazepine C

ChEBI IDCHEBI:221260
ChEBI NameLimazepine C
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC15H16N2O3
Net Charge0
Average Mass272.304
Monoisotopic Mass272.11609
SMILESCCC1=CN2C(=O)c3ccc(OC)c(O)c3N=C[C@@H]2C1
InChIInChI=1S/C15H16N2O3/c1-3-9-6-10-7-16-13-11(15(19)17(10)8-9)4-5-12(20-2)14(13)18/h4-5,7-8,10,18H,3,6H2,1-2H3/t10-/m0/s1
InChIKeyFLGURYUVNVBBFP-JTQLQIEISA-N
Species of MetaboliteComponentSourceComments
Micrococcus (ncbitaxon:1269) - PubMed (19388705)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Limazepine C (CHEBI:221260) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(6aS)-8-ethyl-4-hydroxy-3-methoxy-6a,7-dihydropyrrolo[2,1-c][1,4]benzodiazepin-11-one
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