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CHEBI:219736 - Limazepine B2

ChEBI IDCHEBI:219736
ChEBI NameLimazepine B2
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC15H18N2O4
Net Charge0
Average Mass290.319
Monoisotopic Mass290.12666
SMILESCCC1=CN2C(=O)c3ccc(OC)c(O)c3N[C@@H](O)[C@@H]2C1
InChIInChI=1S/C15H18N2O4/c1-3-8-6-10-14(19)16-12-9(15(20)17(10)7-8)4-5-11(21-2)13(12)18/h4-5,7,10,14,16,18-19H,3,6H2,1-2H3/t10-,14-/m0/s1
InChIKeyYKBYRAOPZZWMOE-HZMBPMFUSA-N
Species of MetaboliteComponentSourceComments
Micrococcus (ncbitaxon:1269) - PubMed (19388705)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Limazepine B2 (CHEBI:219736) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(6S,6aS)-8-ethyl-4,6-dihydroxy-3-methoxy-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one
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