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CHEBI:215486 - Fischeramide B

ChEBI IDCHEBI:215486
ChEBI NameFischeramide B
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC24H23N3O2
Net Charge0
Average Mass385.467
Monoisotopic Mass385.17903
SMILESC=CC(C)(C)c1nc2ccccc2c1/C=C1/C(=O)Nc2ccccc2C(=O)N1C
InChIInChI=1S/C24H23N3O2/c1-5-24(2,3)21-17(15-10-6-8-12-18(15)25-21)14-20-22(28)26-19-13-9-7-11-16(19)23(29)27(20)4/h5-14,25H,1H2,2-4H3,(H,26,28)/b20-14-
InChIKeyDLKHYDICDGRHSE-ZHZULCJRSA-N
Species of MetaboliteComponentSourceComments
Aspergillus fischeri (ncbitaxon:36630) - PubMed (32315839)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Fischeramide B (CHEBI:215486) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(3Z)-4-methyl-3-[[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methylidene]-1H-1,4-benzodiazepine-2,5-dione