EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:28492 - 5-methylbarbituric acid
| Formula | C5H6N2O3 |
| Net Charge | 0 |
| Average Mass | 142.114 |
| Monoisotopic Mass | 142.03784 |
| SMILES | CC1C(=O)NC(=O)NC1=O |
| InChI | InChI=1S/C5H6N2O3/c1-2-3(8)6-5(10)7-4(2)9/h2H,1H3,(H2,6,7,8,9,10) |
| InChIKey | GOMAEJQBTWAPAN-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| 5-methylbarbituric acid (CHEBI:28492) is a barbiturates (CHEBI:22693) |
| 5-methylbarbituric acid (CHEBI:28492) is conjugate acid of 5-methylbarbituride (CHEBI:58571) |
| Incoming Relation(s) |
| 5-methylbarbituride (CHEBI:58571) is conjugate base of 5-methylbarbituric acid (CHEBI:28492) |
| IUPAC Name |
|---|
| 5-methylpyrimidine-2,4,6(1H,3H,5H)-trione |
| Synonyms | Source |
|---|---|
| 5-Methylbarbiturate | KEGG COMPOUND |
| 5-methylbarbituric acid | ChemIDplus |
| 5-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione | ChemIDplus |
| 5-Methylbarbituric acid | KEGG COMPOUND |