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CHEBI:207346 - (−)-FR901483
| Formula | C20H31N2O6P |
| Net Charge | 0 |
| Average Mass | 426.450 |
| Monoisotopic Mass | 426.19197 |
| SMILES | [H][C@]12C[C@@]3(CC[C@@H]1OP(=O)(O)O)C[C@H](NC)CN3[C@@H](Cc1ccc(OC)cc1)[C@H]2O |
| InChI | InChI=1S/C20H31N2O6P/c1-21-14-10-20-8-7-18(28-29(24,25)26)16(11-20)19(23)17(22(20)12-14)9-13-3-5-15(27-2)6-4-13/h3-6,14,16-19,21,23H,7-12H2,1-2H3,(H2,24,25,26)/t14-,16-,17-,18-,19-,20+/m0/s1 |
| InChIKey | CIISYBZFZSWZLX-KKMIJOEASA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Cladobotryum sp. (ncbitaxon:2040732) | - | PubMed (8609083) | Strain: 11231 |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. |
| Application: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (−)-FR901483 (CHEBI:207346) has role fungal metabolite (CHEBI:76946) |
| (−)-FR901483 (CHEBI:207346) has role immunosuppressive agent (CHEBI:35705) |
| (−)-FR901483 (CHEBI:207346) is a monomethoxybenzene (CHEBI:25235) |
| (−)-FR901483 (CHEBI:207346) is a organic heterotricyclic compound (CHEBI:26979) |
| (−)-FR901483 (CHEBI:207346) is a organic phosphate (CHEBI:25703) |
| (−)-FR901483 (CHEBI:207346) is a secondary alcohol (CHEBI:35681) |
| (−)-FR901483 (CHEBI:207346) is a secondary amino compound (CHEBI:50995) |
| (−)-FR901483 (CHEBI:207346) is conjugate acid of (−)-FR901483(2−) (CHEBI:233173) |
| Incoming Relation(s) |
| (−)-FR901483(2−) (CHEBI:233173) is conjugate base of (−)-FR901483 (CHEBI:207346) |
| IUPAC Name |
|---|
| (2S,5S,6S,7R,8S,10aS)-6-hydroxy-5-(4-methoxybenzyl)-2-(methylamino)octahydro-1H-7,10a-methanopyrrolo[1,2-a]azocin-8-yl dihydrogen phosphate |
| Synonyms | Source |
|---|---|
| FR 901483 | ChEBI |
| FR-901483 | ChEBI |
| FR901483 | ChEBI |
| Citations |
|---|