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CHEBI:207346 - (−)-FR901483
| Formula | C20H31N2O6P |
| Net Charge | 0 |
| Average Mass | 426.450 |
| Monoisotopic Mass | 426.19197 |
| SMILES | [H][C@]12C[C@@]3(CC[C@@H]1OP(=O)(O)O)C[C@H](NC)CN3[C@@H](Cc1ccc(OC)cc1)[C@H]2O |
| InChI | InChI=1S/C20H31N2O6P/c1-21-14-10-20-8-7-18(28-29(24,25)26)16(11-20)19(23)17(22(20)12-14)9-13-3-5-15(27-2)6-4-13/h3-6,14,16-19,21,23H,7-12H2,1-2H3,(H2,24,25,26)/t14-,16-,17-,18-,19-,20+/m0/s1 |
| InChIKey | CIISYBZFZSWZLX-KKMIJOEASA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Cladobotryum sp. (ncbitaxon:2040732) | - | PubMed (8609083) | Strain: 11231 |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Application: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (−)-FR901483 (CHEBI:207346) has role fungal metabolite (CHEBI:76946) |
| (−)-FR901483 (CHEBI:207346) has role immunosuppressive agent (CHEBI:35705) |
| (−)-FR901483 (CHEBI:207346) is a monomethoxybenzene (CHEBI:25235) |
| (−)-FR901483 (CHEBI:207346) is a organic heterotricyclic compound (CHEBI:26979) |
| (−)-FR901483 (CHEBI:207346) is a organic phosphate (CHEBI:25703) |
| (−)-FR901483 (CHEBI:207346) is a secondary alcohol (CHEBI:35681) |
| (−)-FR901483 (CHEBI:207346) is a secondary amino compound (CHEBI:50995) |
| (−)-FR901483 (CHEBI:207346) is conjugate acid of (−)-FR901483(2−) (CHEBI:233173) |
| Incoming Relation(s) |
| (−)-FR901483(2−) (CHEBI:233173) is conjugate base of (−)-FR901483 (CHEBI:207346) |
| IUPAC Name |
|---|
| (2S,5S,6S,7R,8S,10aS)-6-hydroxy-5-(4-methoxybenzyl)-2-(methylamino)octahydro-1H-7,10a-methanopyrrolo[1,2-a]azocin-8-yl dihydrogen phosphate |
| Synonyms | Source |
|---|---|
| FR901483 | ChEBI |
| FR-901483 | ChEBI |
| FR 901483 | ChEBI |
| Citations |
|---|