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CHEBI:204734 - desonide

ChEBI IDCHEBI:204734
ChEBI Namedesonide
Stars
DefinitionTriamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders.
Last Modified6 February 2018
DownloadsMolfile
FormulaC24H32O6
Net Charge0
Average Mass416.514
Monoisotopic Mass416.21989
SMILES[H][C@@]12C[C@H]3OC(C)(C)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C
InChIInChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1
InChIKeyWBGKWQHBNHJJPZ-LECWWXJVSA-N
Wikipedia
Roles Classification
Application:
anti-inflammatory drug  A substance that reduces or suppresses inflammation.
ChEBI Ontology
Outgoing Relation(s)
desonide (CHEBI:204734) has role anti-inflammatory drug (CHEBI:35472)
desonide (CHEBI:204734) is a 11β-hydroxy steroid (CHEBI:35346)
desonide (CHEBI:204734) is a 20-oxo steroid (CHEBI:36885)
desonide (CHEBI:204734) is a 21-hydroxy steroid (CHEBI:35344)
desonide (CHEBI:204734) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166)
desonide (CHEBI:204734) is a corticosteroid (CHEBI:50858)
desonide (CHEBI:204734) is a cyclic ketal (CHEBI:59779)
desonide (CHEBI:204734) is a primary α-hydroxy ketone (CHEBI:139590)
IUPAC Name 
(4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
INNs  Source
desonidaChemIDplus
desonideChemIDplus
desonidumChemIDplus
Synonyms  Source
16α-hydroxyprednisole-16,17-acetonideChemIDplus
11β,21-dihydroxy-16α,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dioneChEBI
16α-hydroxyprednisolone-16α,17-acetonideChEBI
11β,21-dihydroxy-16α,17-isopropylidenedioxypregna-1,4-diene-3,20-dioneChEBI
16α,17α-isopropylidenedioxyprednisoloneChEBI
11β,21-dihydroxy-16α,17α-isopropylidenedioxypregna-1,4-diene-3,20-dioneChEBI
Manual XrefsDatabases
D03696KEGG DRUG
DB01260DrugBank
US2990401Patent
US3536586Patent
US3549498Patent
DesonideWikipedia
3135DrugCentral
Registry NumbersSources
Beilstein:56987Beilstein
CAS:638-94-8KEGG DRUG
CAS:638-94-8ChemIDplus
Citations