EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:204330 - Limazepine A

ChEBI IDCHEBI:204330
ChEBI NameLimazepine A
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC15H16N2O4
Net Charge0
Average Mass288.303
Monoisotopic Mass288.11101
SMILESCCC1=CN2C(=O)c3ccc(OC)c(O)c3NC(=O)[C@@H]2C1
InChIInChI=1S/C15H16N2O4/c1-3-8-6-10-14(19)16-12-9(15(20)17(10)7-8)4-5-11(21-2)13(12)18/h4-5,7,10,18H,3,6H2,1-2H3,(H,16,19)/t10-/m0/s1
InChIKeyWFFPORSPDSBCLL-JTQLQIEISA-N
Species of MetaboliteComponentSourceComments
Micrococcus (ncbitaxon:1269) - PubMed (19388705)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Limazepine A (CHEBI:204330) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(6aS)-8-ethyl-4-hydroxy-3-methoxy-6a,7-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-6,11-dione
Manual XrefsDatabases
24625714ChemSpider