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CHEBI:204009 - Porothramycin A

ChEBI IDCHEBI:204009
ChEBI NamePorothramycin A
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC18H21N3O4
Net Charge0
Average Mass343.383
Monoisotopic Mass343.15321
SMILESCOc1cccc2c1N[C@H](O)[C@@H]1CC(/C=C/C(=O)N(C)C)=CN1C2=O
InChIInChI=1S/C18H21N3O4/c1-20(2)15(22)8-7-11-9-13-17(23)19-16-12(18(24)21(13)10-11)5-4-6-14(16)25-3/h4-8,10,13,17,19,23H,9H2,1-3H3/b8-7+/t13-,17+/m0/s1
InChIKeyOQMYRVPMCIOFHL-UDBCLFQLSA-N
Species of MetaboliteComponentSourceComments
Streptomyces (ncbitaxon:1883) - PubMed (3192492)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Porothramycin A (CHEBI:204009) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(E)-3-[(6R,6aS)-6-hydroxy-4-methoxy-11-oxo-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]-N,N-dimethylprop-2-enamide
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