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CHEBI:198993 - Porothramycin B

ChEBI IDCHEBI:198993
ChEBI NamePorothramycin B
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC19H23N3O4
Net Charge0
Average Mass357.410
Monoisotopic Mass357.16886
SMILESCOc1cccc2c1N[C@H](OC)[C@@H]1CC(C=CC(=O)N(C)C)=CN1C2=O
InChIInChI=1S/C19H23N3O4/c1-21(2)16(23)9-8-12-10-14-18(26-4)20-17-13(19(24)22(14)11-12)6-5-7-15(17)25-3/h5-9,11,14,18,20H,10H2,1-4H3/t14-,18+/m0/s1
InChIKeyXCFSBOSFMAOQAL-KBXCAEBGSA-N
Species of MetaboliteComponentSourceComments
Streptomyces (ncbitaxon:1883) - PubMed (3192492)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Porothramycin B (CHEBI:198993) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
3-[(6R,6aS)-4,6-dimethoxy-11-oxo-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-8-yl]-N,N-dimethylprop-2-enamide