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CHEBI:198932 - Limazepine F

ChEBI IDCHEBI:198932
ChEBI NameLimazepine F
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SubmitterMetaboLights
DownloadsMolfile
FormulaC14H16N2O2
Net Charge0
Average Mass244.294
Monoisotopic Mass244.12118
SMILESC/C=C1\C[C@H]2[C@@H](O)Nc3ccccc3C(=O)N2C1
InChIInChI=1S/C14H16N2O2/c1-2-9-7-12-13(17)15-11-6-4-3-5-10(11)14(18)16(12)8-9/h2-6,12-13,15,17H,7-8H2,1H3/b9-2+/t12-,13+/m0/s1
InChIKeyULQQQQMOGBDJEB-PHVGEZJSSA-N
Species of MetaboliteComponentSourceComments
Micrococcus (ncbitaxon:1269) - PubMed (19388705)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Limazepine F (CHEBI:198932) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
(6R,6aS,8E)-8-ethylidene-6-hydroxy-6,6a,7,9-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-11-one
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