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CHEBI:197522 - MSVIII-19

ChEBI IDCHEBI:197522
ChEBI NameMSVIII-19
Stars
DefinitionA furopyran that is (3aR,7aR)-hexahydro-2H-furo[3,2-b]pyran substituted by carboxy and (2S)-2-amino-2-carboxyethyl groups at position 2 (the 2R,3aR,7aR-stereoisomer). It is an antagonist of the kainate-type ionotropic receptor, GluK1.
Last Modified1 November 2023
Submittersbalu
DownloadsMolfile
FormulaC11H17NO6
Net Charge0
Average Mass259.258
Monoisotopic Mass259.10559
SMILES[H][C@@]12C[C@](C[C@H](N)C(=O)O)(C(=O)O)O[C@]1([H])CCCO2
InChIInChI=1S/C11H17NO6/c12-6(9(13)14)4-11(10(15)16)5-8-7(18-11)2-1-3-17-8/h6-8H,1-5,12H2,(H,13,14)(H,15,16)/t6-,7+,8+,11+/m0/s1
InChIKeyRZIYCCQNKHONBB-PRKAOEEVSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
excitatory amino acid antagonist  Any substance which inhibits the action of receptors for excitatory amino acids.
antinociceptive agent  Any agent that inhibits nociception.
Application:
antinociceptive agent  Any agent that inhibits nociception.
ChEBI Ontology
Outgoing Relation(s)
MSVIII-19 (CHEBI:197522) has role antinociceptive agent (CHEBI:228138)
MSVIII-19 (CHEBI:197522) has role excitatory amino acid antagonist (CHEBI:60798)
MSVIII-19 (CHEBI:197522) is a amino dicarboxylic acid (CHEBI:36164)
MSVIII-19 (CHEBI:197522) is a furopyran (CHEBI:74927)
IUPAC Name 
(2R,3aR,7aR)-2-[(2S)-2-amino-2-carboxyethyl]hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid
Synonyms  Source
8,9-dideoxyneodysiherbaineSUBMITTER
2-amino-4,7:6,10-dianhydro-4-carboxy-2,3,5,8,9-pentadeoxy-D-talo-deconic acidIUPAC
8,9-dideoxy-NDHChEBI
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