EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:16810 - 2-oxoglutarate(2−)

ChEBI IDCHEBI:16810
ChEBI Name2-oxoglutarate(2−)
Stars
ASCII Name2-oxoglutarate(2-)
DefinitionAn oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid.
Secondary ChEBI IDsCHEBI:11638, CHEBI:19748
Last Modified28 October 2021
DownloadsMolfile
FormulaC5H4O5
Net Charge-2
Average Mass144.082
Monoisotopic Mass144.00697
SMILESO=C([O-])CCC(=O)C(=O)[O-]
InChIInChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/p-2
InChIKeyKPGXRSRHYNQIFN-UHFFFAOYSA-L
Species of MetaboliteComponentSourceComments
Chlamydomonas reinhardtii (ncbitaxon:3055) - PubMed (25515814)
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Saccharomyces cerevisiae (ncbitaxon:4932) - PubMed (24678285) Source: yeast.sf.net
Roles Classification
Biological Roles:
algal metabolite  Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
Saccharomyces cerevisiae metabolite  Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Application:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ChEBI Ontology
Outgoing Relation(s)
2-oxoglutarate(2−) (CHEBI:16810) has functional parent glutarate(2−) (CHEBI:30921)
2-oxoglutarate(2−) (CHEBI:16810) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
2-oxoglutarate(2−) (CHEBI:16810) has role algal metabolite (CHEBI:84735)
2-oxoglutarate(2−) (CHEBI:16810) has role geroprotector (CHEBI:176497)
2-oxoglutarate(2−) (CHEBI:16810) has role human metabolite (CHEBI:77746)
2-oxoglutarate(2−) (CHEBI:16810) is a oxo dicarboxylate (CHEBI:36147)
2-oxoglutarate(2−) (CHEBI:16810) is conjugate base of 2-oxoglutarate(1−) (CHEBI:30916)
Incoming Relation(s)
2-oxoglutarate(1−) (CHEBI:30916) is conjugate acid of 2-oxoglutarate(2−) (CHEBI:16810)
IUPAC Name 
2-oxopentanedioate
Synonyms  Source
2-ketoglutarateChEBI
2-oxopentanedioic acid, ion(2−)ChemIDplus
α-ketoglutarateChEBI
UniProt Name  Source
2-oxoglutarateUniProt
Manual XrefsDatabases
2-KETOGLUTARATEMetaCyc
C00026KEGG COMPOUND
Registry NumbersSources
Reaxys:3664503Reaxys
Gmelin:602479Gmelin
CAS:64-15-3ChemIDplus
Citations