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CHEBI:196363 - 4'-Hydroxyclobazam

ChEBI IDCHEBI:196363
ChEBI Name4'-Hydroxyclobazam
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC16H13ClN2O3
Net Charge0
Average Mass316.744
Monoisotopic Mass316.06147
SMILESCN1C(=O)CC(=O)N(c2ccc(O)cc2)c2cc(Cl)ccc21
InChIInChI=1S/C16H13ClN2O3/c1-18-13-7-2-10(17)8-14(13)19(16(22)9-15(18)21)11-3-5-12(20)6-4-11/h2-8,20H,9H2,1H3
InChIKeyNKSXJAYACJZMBM-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
4'-Hydroxyclobazam (CHEBI:196363) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
7-chloro-5-(4-hydroxyphenyl)-1-methyl-1,5-benzodiazepine-2,4-dione
Manual XrefsDatabases
30778586ChemSpider
HMDB0060771HMDB