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CHEBI:194340 - apinocaltamide
| Formula | C22H18F3N5O |
| Net Charge | 0 |
| Average Mass | 425.414 |
| Monoisotopic Mass | 425.14634 |
| SMILES | N#Cc1ccc(Cn2ccc(NC(=O)Cc3ccc(C4(C(F)(F)F)CC4)cc3)n2)nc1 |
| InChI | InChI=1S/C22H18F3N5O/c23-22(24,25)21(8-9-21)17-4-1-15(2-5-17)11-20(31)28-19-7-10-30(29-19)14-18-6-3-16(12-26)13-27-18/h1-7,10,13H,8-9,11,14H2,(H,28,29,31) |
| InChIKey | LSYANGLAZUZYFX-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | T-type calcium channel blocker Any agent that interferes with the activity of T-type calcium channels. |
| Application: | anticonvulsant A drug used to prevent seizures or reduce their severity. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| apinocaltamide (CHEBI:194340) has role anticonvulsant (CHEBI:35623) |
| apinocaltamide (CHEBI:194340) has role T-type calcium channel blocker (CHEBI:194338) |
| apinocaltamide (CHEBI:194340) is a benzenes (CHEBI:22712) |
| apinocaltamide (CHEBI:194340) is a cyclopropanes (CHEBI:51454) |
| apinocaltamide (CHEBI:194340) is a nitrile (CHEBI:18379) |
| apinocaltamide (CHEBI:194340) is a organofluorine compound (CHEBI:37143) |
| apinocaltamide (CHEBI:194340) is a pyrazoles (CHEBI:26410) |
| apinocaltamide (CHEBI:194340) is a pyridines (CHEBI:26421) |
| apinocaltamide (CHEBI:194340) is a secondary carboxamide (CHEBI:140325) |
| IUPAC Name |
|---|
| N-{1-[(5-cyanopyridin-2-yl)methyl]-1H-pyrazol-3-yl}-2-{4-[1-(trifluoromethyl)cyclopropyl]phenyl}acetamide |
| INNs | Source |
|---|---|
| apinocaltamide | WHO MedNet |
| apinocaltamide | WHO MedNet |
| apinocaltamidum | WHO MedNet |
| apinocaltamida | WHO MedNet |
| Synonyms | Source |
|---|---|
| ACT 709478 | ChEBI |
| ACT709478 | ChEBI |
| ACT-709478 | ChEBI |
| N-[1-[(5-cyano-2-pyridinyl)methyl]-1H-pyrazol-3-yl]-4-[1-(trifluoromethyl)cyclopropyl]-benzeneacetamide | ChEBI |
| Citations |
|---|