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CHEBI:192693 - (3S)-3-(1H-Indol-3-ylmethyl)-3H-1,4-benzodiazepine-2,5-diol

ChEBI IDCHEBI:192693
ChEBI Name(3S)-3-(1H-Indol-3-ylmethyl)-3H-1,4-benzodiazepine-2,5-diol
Stars
ASCII Name(3S)-3-(1H-Indol-3-ylmethyl)-3H-1,4-benzodiazepine-2,5-diol
SubmitterAnne Morgat
DownloadsMolfile
FormulaC18H15N3O2
Net Charge0
Average Mass305.337
Monoisotopic Mass305.11643
SMILESO=C1N[C@@H](Cc2cnc3ccccc23)C(=O)Nc2ccccc21
InChIInChI=1S/C18H15N3O2/c22-17-13-6-2-4-8-15(13)20-18(23)16(21-17)9-11-10-19-14-7-3-1-5-12(11)14/h1-8,10,16,19H,9H2,(H,20,23)(H,21,22)/t16-/m0/s1
InChIKeyAQDZAHJUWYRHGM-INIZCTEOSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
(3S)-3-(1H-Indol-3-ylmethyl)-3H-1,4-benzodiazepine-2,5-diol (CHEBI:192693) is a benzodiazepine (CHEBI:22720)
UniProt Name  Source
(S)-benzodiazepinedioneUniProt
Citations