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CHEBI:190989 - 3-methyl-3,4-dihydro-1h-1,4-benzodiazepine-2,5-dione

Default Structure
ChEBI IDCHEBI:190989
ChEBI Name3-methyl-3,4-dihydro-1h-1,4-benzodiazepine-2,5-dione
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC10H10N2O2
Net Charge0
Average Mass190.202
Monoisotopic Mass190.07423
SMILESCC1NC(=O)c2ccccc2NC1=O
InChIInChI=1S/C10H10N2O2/c1-6-9(13)12-8-5-3-2-4-7(8)10(14)11-6/h2-6H,1H3,(H,11,14)(H,12,13)
InChIKeyLJONQULKOKMKBR-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Rattus norvegicus (ncbitaxon:10116) INS-1 cell (BTO:0002135) MetaboLights (MTBLS3963)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
3-methyl-3,4-dihydro-1h-1,4-benzodiazepine-2,5-dione (CHEBI:190989) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
3-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione
Manual XrefsDatabases
3436217ChemSpider