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CHEBI:190616 - N-Desmethylclobazam

ChEBI IDCHEBI:190616
ChEBI NameN-Desmethylclobazam
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC15H11ClN2O2
Net Charge0
Average Mass286.718
Monoisotopic Mass286.05091
SMILESO=C1CC(=O)N(c2ccccc2)c2cc(Cl)ccc2N1
InChIInChI=1S/C15H11ClN2O2/c16-10-6-7-12-13(8-10)18(11-4-2-1-3-5-11)15(20)9-14(19)17-12/h1-8H,9H2,(H,17,19)
InChIKeyRRTVVRIFVKKTJK-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Rattus norvegicus (ncbitaxon:10116) liver (BTO:0000759) MetaboLights (MTBLS4163)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
N-Desmethylclobazam (CHEBI:190616) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
7-chloro-5-phenyl-1H-1,5-benzodiazepine-2,4-dione
Manual XrefsDatabases
80921ChemSpider
HMDB0060970HMDB
Registry NumbersSources
CAS:22316-55-8ChemIDplus