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CHEBI:190610 - 1-(2,4-diphenyl-2,3-dihydro-1H-1,5-benzodiazepin-1-yl)propan-1-one

ChEBI IDCHEBI:190610
ChEBI Name1-(2,4-diphenyl-2,3-dihydro-1H-1,5-benzodiazepin-1-yl)propan-1-one
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC24H22N2O
Net Charge0
Average Mass354.453
Monoisotopic Mass354.17321
SMILESCCC(=O)N1c2ccccc2N=C(c2ccccc2)CC1c1ccccc1
InChIInChI=1S/C24H22N2O/c1-2-24(27)26-22-16-10-9-15-20(22)25-21(18-11-5-3-6-12-18)17-23(26)19-13-7-4-8-14-19/h3-16,23H,2,17H2,1H3
InChIKeyQANWFXLRXJOXFE-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Rattus norvegicus (ncbitaxon:10116) liver (BTO:0000759) MetaboLights (MTBLS4163)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
1-(2,4-diphenyl-2,3-dihydro-1H-1,5-benzodiazepin-1-yl)propan-1-one (CHEBI:190610) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
1-(2,4-diphenyl-2,3-dihydro-1,5-benzodiazepin-1-yl)propan-1-one
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