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CHEBI:189865 - C75
| ChEBI ID | CHEBI:189865 |
| ChEBI Name | C75 |
| Stars | |
| Definition | A racemate comprising equimolar amount of (2R,3S)-C75 and its enantiomer, (2S,3R)-C75. It is a fatty-acid synthase (FAS) inhibitor and an activator of carnitine palmitoyl-transferase-1 that leads to weight loss and feeding inhibition in mice. |
| Last Modified | 12 May 2022 |
| Submitter | slaulederkind |
| Formula | |
| Net Charge | 0 |
| Average Mass | 254.326 |
| Monoisotopic Mass | 254.15181 |
| Roles Classification |
|---|
| Biological Roles: | apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. anti-obesity agent Any substance which is used to reduce or control weight. EC 2.3.1.85 (fatty acid synthase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis. fatty acid synthesis inhibitor Any pathway inhibitor that inhibits the synthesis of fatty acids. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| C75 (CHEBI:189865) has part (2R,3S)-C75 (CHEBI:191400) |
| C75 (CHEBI:189865) has part (2S,3R)-C75 (CHEBI:191401) |
| C75 (CHEBI:189865) has role anti-obesity agent (CHEBI:74518) |
| C75 (CHEBI:189865) has role antineoplastic agent (CHEBI:35610) |
| C75 (CHEBI:189865) has role apoptosis inducer (CHEBI:68495) |
| C75 (CHEBI:189865) has role EC 2.3.1.85 (fatty acid synthase) inhibitor (CHEBI:71476) |
| C75 (CHEBI:189865) has role fatty acid synthesis inhibitor (CHEBI:50185) |
| C75 (CHEBI:189865) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-(2R,3S)-4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid |
| Synonyms | Source |
|---|---|
| trans-C75 | SUBMITTER |
| (±)-C75 | SUBMITTER |
| C75 trans | SUBMITTER |
| trans-C 75 | ChemIDplus |
| (2R*,3S*)-tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid | ChEBI |
| (2R*,3S*)-4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid | ChEBI |
| Registry Numbers | Sources |
|---|---|
| CAS:191282-48-1 | ChemIDplus |
| Citations |
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