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CHEBI:189865 - C75
| ChEBI ID | CHEBI:189865 |
| ChEBI Name | C75 |
| Stars | |
| Definition | A racemate comprising equimolar amount of (2R,3S)-C75 and its enantiomer, (2S,3R)-C75. It is a fatty-acid synthase (FAS) inhibitor and an activator of carnitine palmitoyl-transferase-1 that leads to weight loss and feeding inhibition in mice. |
| Last Modified | 12 May 2022 |
| Submitter | slaulederkind |
| Formula | |
| Net Charge | 0 |
| Average Mass | 254.326 |
| Monoisotopic Mass | 254.15181 |
| Roles Classification |
|---|
| Biological Roles: | EC 2.3.1.85 (fatty acid synthase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis. anti-obesity agent Any substance which is used to reduce or control weight. fatty acid synthesis inhibitor Any pathway inhibitor that inhibits the synthesis of fatty acids. apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| C75 (CHEBI:189865) has part (2R,3S)-C75 (CHEBI:191400) |
| C75 (CHEBI:189865) has part (2S,3R)-C75 (CHEBI:191401) |
| C75 (CHEBI:189865) has role anti-obesity agent (CHEBI:74518) |
| C75 (CHEBI:189865) has role antineoplastic agent (CHEBI:35610) |
| C75 (CHEBI:189865) has role apoptosis inducer (CHEBI:68495) |
| C75 (CHEBI:189865) has role EC 2.3.1.85 (fatty acid synthase) inhibitor (CHEBI:71476) |
| C75 (CHEBI:189865) has role fatty acid synthesis inhibitor (CHEBI:50185) |
| C75 (CHEBI:189865) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-(2R,3S)-4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid |
| Synonyms | Source |
|---|---|
| (2R*,3S*)-4-methylidene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid | ChEBI |
| (2R*,3S*)-tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid | ChEBI |
| (±)-C75 | SUBMITTER |
| C75 trans | SUBMITTER |
| C75 (racemic mixture of trans-isomers) | ChEBI |
| trans-C 75 | ChemIDplus |
| Registry Numbers | Sources |
|---|---|
| CAS:191282-48-1 | ChemIDplus |
| Citations |
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