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CHEBI:188885 - Flutemazepam

ChEBI IDCHEBI:188885
ChEBI NameFlutemazepam
Stars
Last Modified17 March 2025
SubmitterMetaboLights
DownloadsMolfile
FormulaC16H12ClFN2O2
Net Charge0
Average Mass318.735
Monoisotopic Mass318.05713
SMILESCN1C(=O)C(O)N=C(c2ccccc2F)c2cc(Cl)ccc21
InChIInChI=1S/C16H12ClFN2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3
InChIKeyRMFYWNFETXNTIQ-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Phyllostachys violascens (ncbitaxon:1903417) stem (BTO:0001300) MetaboLights (MTBLS3970) Strain: Phyllostachys violascens cv. Viridisulcata
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
Flutemazepam (CHEBI:188885) is a benzodiazepine (CHEBI:22720)
IUPAC Name 
7-chloro-5-(2-fluorophenyl)-3-hydroxy-1-methyl-3H-1,4-benzodiazepin-2-one
Manual XrefsDatabases
36859ChemSpider
Registry NumbersSources
CAS:52391-89-6ChemIDplus