EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:183514 - psora 4

Default Structure
ChEBI IDCHEBI:183514
ChEBI Namepsora 4
Stars
DefinitionA member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel Kv1.3 (EC50 = 3 nM).
Last Modified9 November 2021
SubmitterAdnan
DownloadsMolfile
FormulaC21H18O4
Net Charge0
Average Mass334.371
Monoisotopic Mass334.12051
SMILESO=c1ccc2c(OCCCCc3ccccc3)c3ccoc3cc2o1
InChIInChI=1S/C21H18O4/c22-20-10-9-16-19(25-20)14-18-17(11-13-23-18)21(16)24-12-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-11,13-14H,4-5,8,12H2
InChIKeyJJAWGNIQEOFURP-UHFFFAOYSA-N
Roles Classification
Biological Roles:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
potassium channel blocker  An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
Applications:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
ChEBI Ontology
Outgoing Relation(s)
psora 4 (CHEBI:183514) has role geroprotector (CHEBI:176497)
psora 4 (CHEBI:183514) has role immunosuppressive agent (CHEBI:35705)
psora 4 (CHEBI:183514) has role potassium channel blocker (CHEBI:50509)
psora 4 (CHEBI:183514) is a aromatic ether (CHEBI:35618)
psora 4 (CHEBI:183514) is a benzenes (CHEBI:22712)
psora 4 (CHEBI:183514) is a psoralens (CHEBI:26369)
IUPAC Name 
4-(4-phenylbutoxy)-7H-furo[3,2-g]chromen-7-one
Synonyms  Source
4-(4-phenylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-oneIUPAC
5-(4-phenylbutoxy)psoralenChEBI
psora-4ChEBI
Manual XrefsDatabases
5036283ChemSpider
HMDB0256900HMDB
Registry NumbersSources
CAS:724709-68-6ChEBI
Citations