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CHEBI:183514 - psora 4

ChEBI IDCHEBI:183514
ChEBI Namepsora 4
Stars
DefinitionA member of the class of psoralens that is psoralen substituted by a 4-phenylbutoxy group at position 5. It is a potent inhibitor of the voltage-gated potassium channel Kv1.3 (EC50 = 3 nM).
Last Modified9 November 2021
SubmitterAdnan
DownloadsMolfile
FormulaC21H18O4
Net Charge0
Average Mass334.371
Monoisotopic Mass334.12051
SMILESO=c1ccc2c(OCCCCc3ccccc3)c3ccoc3cc2o1
InChIInChI=1S/C21H18O4/c22-20-10-9-16-19(25-20)14-18-17(11-13-23-18)21(16)24-12-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-11,13-14H,4-5,8,12H2
InChIKeyJJAWGNIQEOFURP-UHFFFAOYSA-N
Roles Classification
Biological Roles:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
potassium channel blocker  An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
Applications:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
ChEBI Ontology
Outgoing Relation(s)
psora 4 (CHEBI:183514) has role geroprotector (CHEBI:176497)
psora 4 (CHEBI:183514) has role immunosuppressive agent (CHEBI:35705)
psora 4 (CHEBI:183514) has role potassium channel blocker (CHEBI:50509)
psora 4 (CHEBI:183514) is a aromatic ether (CHEBI:35618)
psora 4 (CHEBI:183514) is a benzenes (CHEBI:22712)
psora 4 (CHEBI:183514) is a psoralens (CHEBI:26369)
IUPAC Name 
4-(4-phenylbutoxy)-7H-furo[3,2-g]chromen-7-one
Synonyms  Source
4-(4-phenylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-oneIUPAC
psora-4ChEBI
5-(4-phenylbutoxy)psoralenChEBI
Manual XrefsDatabases
5036283ChemSpider
HMDB0256900HMDB
Registry NumbersSources
CAS:724709-68-6ChEBI
Citations