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CHEBI:180658 - actinomycin X2

Default Structure
ChEBI IDCHEBI:180658
ChEBI Nameactinomycin X2
Stars
DefinitionActinomycin X2, is a chemotherapy medication used to treat a number of types of cancer and has strong antimicrobial activity against Gram-positive bacteria, including MRSA and non-MRSA. It is given by injection into a vein. Most people develop side effects. Common side effects include bone marrow suppression, vomiting, mouth ulcers, hair loss, liver problems, infections, and muscle pains. Other serious side effects include future cancers, allergic reactions, and tissue death at the site of injection. Use in pregnancy may harm the baby. It is in the cytotoxic antibiotic family of medications. It is believed to work on DNA and Isoleucyl-tRNA synthetase (IleRS).
Last Modified5 December 2022
SubmitterTahlil.Afrah
DownloadsMolfile
FormulaC62H84N12O17
Net Charge0
Average Mass1269.421
Monoisotopic Mass1268.60774
SMILES[H][C@@]12CCCN1C(=O)[C@@H](C(C)C)NC(=O)[C@@H](NC(=O)c1c3nc4c(C(=O)N[C@@H]5C(=O)N[C@H](C(C)C)C(=O)N6CC(=O)C[C@@]6([H])C(=O)N(C)CC(=O)N(C)[C@@H](C(C)C)C(=O)O[C@@H]5C)ccc(C)c4oc-3c(C)c(=O)c1N)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O
InChIInChI=1S/C62H84N12O17/c1-26(2)42-59(85)73-21-17-18-36(73)57(83)69(13)24-38(76)71(15)49(29(7)8)62(88)90-33(12)45(56(82)65-42)68-54(80)40-41(63)50(78)31(10)52-47(40)64-46-35(20-19-30(9)51(46)91-52)53(79)67-44-32(11)89-61(87)48(28(5)6)72(16)39(77)25-70(14)58(84)37-22-34(75)23-74(37)60(86)43(27(3)4)66-55(44)81/h19-20,26-29,32-33,36-37,42-45,48-49H,17-18,21-25,63H2,1-16H3,(H,65,82)(H,66,81)(H,67,79)(H,68,80)/t32-,33-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
InChIKeyZGROOAYIFKLEPE-IRFLANFNSA-N
ChEBI Ontology
Outgoing Relation(s)
actinomycin X2 (CHEBI:180658) is a organic molecular entity (CHEBI:50860)