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CHEBI:180569 - 4-Hydroxyphenobarbital

ChEBI IDCHEBI:180569
ChEBI Name4-Hydroxyphenobarbital
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC12H12N2O4
Net Charge0
Average Mass248.238
Monoisotopic Mass248.07971
SMILESCCC1(c2ccc(O)cc2)C(=O)NC(=O)NC1=O
InChIInChI=1S/C12H12N2O4/c1-2-12(7-3-5-8(15)6-4-7)9(16)13-11(18)14-10(12)17/h3-6,15H,2H2,1H3,(H2,13,14,16,17,18)
InChIKeyIEPXMKJNWPXDBP-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) pancreas (BTO:0000988) MetaboLights (MTBLS1925) Strain: PANC-1 cell [BCGO:0000122]
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
4-Hydroxyphenobarbital (CHEBI:180569) is a barbiturates (CHEBI:22693)
IUPAC Name 
5-ethyl-5-(4-hydroxyphenyl)-1,3-diazinane-2,4,6-trione
Manual XrefsDatabases
9402ChemSpider
HMDB0060537HMDB
Registry NumbersSources
CAS:379-34-0ChemIDplus