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CHEBI:180495 - 4-phenyl-3-furoxancarbonitrile

ChEBI IDCHEBI:180495
ChEBI Name4-phenyl-3-furoxancarbonitrile
Stars
DefinitionA 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation.
Last Modified22 September 2021
SubmitterAdnan
DownloadsMolfile
FormulaC9H5N3O2
Net Charge0
Average Mass187.158
Monoisotopic Mass187.03818
SMILESN#Cc1c(-c2ccccc2)no[n+]1[O-]
InChIInChI=1S/C9H5N3O2/c10-6-8-9(11-14-12(8)13)7-4-2-1-3-5-7/h1-5H
InChIKeyPMYJGTWUVVVOFO-UHFFFAOYSA-N
Roles Classification
Chemical Role:
nitric oxide donor  An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide.
Biological Role:
soluble guanylate cyclase activator  Any compound that binds to and activates soluble guanylate cyclase (EC 4.6.1.2).
Applications:
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
vasodilator agent  A drug used to cause dilation of the blood vessels.
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
ChEBI Ontology
Outgoing Relation(s)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) has role geroprotector (CHEBI:176497)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) has role nitric oxide donor (CHEBI:50566)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) has role platelet aggregation inhibitor (CHEBI:50427)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) has role soluble guanylate cyclase activator (CHEBI:76022)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) has role vasodilator agent (CHEBI:35620)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) is a N-oxide (CHEBI:35580)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) is a 1,2,5-oxadiazole (CHEBI:46815)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) is a benzenes (CHEBI:22712)
4-phenyl-3-furoxancarbonitrile (CHEBI:180495) is a nitrile (CHEBI:18379)
IUPAC Name 
4-phenyl-1,2,5-oxadiazole-3-carbonitrile 2-oxide
Synonyms  Source
RVC-589ChEBI
2-oxo-4-phenyl-1,2,5λ5-oxadiazole-3-carbonitrileIUPAC
3-cyano-4-phenylfurazan 2-oxideChEBI
Manual XrefsDatabases
1692ChemSpider
Registry NumbersSources
CAS:125520-62-9ChEBI
Citations