CHEBI:180485 - amperozide hydrochloride

ChEBI IDCHEBI:180485
ChEBI Nameamperozide hydrochloride
Stars
DefinitionThe hydrochloride salt of amperozide.
Last Modified20 September 2021
SubmitterAdnan
DownloadsMolfile
FormulaC23H29F2N3O.HCl
Net Charge0
Average Mass437.962
Monoisotopic Mass437.20455
SMILESCCNC(=O)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1.Cl
InChIInChI=1S/C23H29F2N3O.ClH/c1-2-26-23(29)28-16-14-27(15-17-28)13-3-4-22(18-5-9-20(24)10-6-18)19-7-11-21(25)12-8-19;/h5-12,22H,2-4,13-17H2,1H3,(H,26,29);1H
InChIKeyOEQHKNWFXHBJIT-UHFFFAOYSA-N
Roles Classification
Biological Roles:
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
Applications:
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
second generation antipsychotic  Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
ChEBI Ontology
Outgoing Relation(s)
amperozide hydrochloride (CHEBI:180485) has part amperozide(1+) (CHEBI:180484)
amperozide hydrochloride (CHEBI:180485) has role anxiolytic drug (CHEBI:35474)
amperozide hydrochloride (CHEBI:180485) has role dopamine uptake inhibitor (CHEBI:51039)
amperozide hydrochloride (CHEBI:180485) has role geroprotector (CHEBI:176497)
amperozide hydrochloride (CHEBI:180485) has role second generation antipsychotic (CHEBI:65191)
amperozide hydrochloride (CHEBI:180485) has role serotonergic antagonist (CHEBI:48279)
amperozide hydrochloride (CHEBI:180485) is a hydrochloride (CHEBI:36807)
IUPAC Name 
4-[4,4-bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide hydrochloride
Synonyms  Source
1-[4,4-bis(4-fluorophenyl)butyl]-4-(ethylcarbamoyl)piperazin-1-ium chlorideIUPAC
amperozide HClChemIDplus
amperozide monohydrochlorideChEBI
4-(4,4-bis(p-fluorophenyl)butyl)-N-ethyl-1-piperazinecarboxamide hydrochlorideChemIDplus
FG 5606ChEBI
FG-5606ChEBI
Brand Name  Source
HogpaxChemIDplus
Manual XrefsDatabases
66063ChemSpider
Registry NumbersSources
CAS:75529-73-6ChemIDplus
CAS:86725-37-3ChemIDplus
Citations