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CHEBI:176399 - inclisiran

ChEBI IDCHEBI:176399
ChEBI Nameinclisiran
Stars
DefinitionInclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against PCSK9. It is indicated for the treatment of primary hypercholesterolemia (familial and non-familial) or mixed dyslipidemia in adults.
Last Modified14 June 2021
SubmitterBijay
Wikipedia
Roles Classification
Applications:
antiatherosclerotic agent  A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
anticholesteremic drug  A substance used to lower plasma cholesterol levels.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
ChEBI Ontology
Outgoing Relation(s)
inclisiran (CHEBI:176399) has role antiatherosclerotic agent (CHEBI:145947)
inclisiran (CHEBI:176399) has role anticholesteremic drug (CHEBI:35821)
inclisiran (CHEBI:176399) has role cardiovascular drug (CHEBI:35554)
inclisiran (CHEBI:176399) has role renoprotective agent (CHEBI:231911)
inclisiran (CHEBI:176399) is a organic molecular entity (CHEBI:50860)
INNs  Source
inclisiranWHO MedNet
inclisiranWHO MedNet
inclisiránWHO MedNet
inclisiranumWHO MedNet
Synonyms  Source
ALN-60212ChemIDplus
ALN-PCSscChemIDplus
ALN-PSCscChEMBL
Brand Name  Source
LeqvioKEGG DRUG
Manual XrefsDatabases
D11931KEGG DRUG
DB14901DrugBank
InclisiranWikipedia
Registry NumbersSources
CAS:1639324-58-5ChemIDplus
Citations