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CHEBI:176399 - inclisiran

ChEBI IDCHEBI:176399
ChEBI Nameinclisiran
Stars
DefinitionInclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against PCSK9. It is indicated for the treatment of primary hypercholesterolemia (familial and non-familial) or mixed dyslipidemia in adults.
Last Modified14 June 2021
SubmitterBijay
Wikipedia
Roles Classification
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
anticholesteremic drug  A substance used to lower plasma cholesterol levels.
antiatherosclerotic agent  A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
ChEBI Ontology
Outgoing Relation(s)
inclisiran (CHEBI:176399) has role antiatherosclerotic agent (CHEBI:145947)
inclisiran (CHEBI:176399) has role anticholesteremic drug (CHEBI:35821)
inclisiran (CHEBI:176399) has role cardiovascular drug (CHEBI:35554)
inclisiran (CHEBI:176399) has role renoprotective agent (CHEBI:231911)
inclisiran (CHEBI:176399) is a organic molecular entity (CHEBI:50860)
INNs  Source
inclisiranWHO MedNet
inclisiranWHO MedNet
inclisiránWHO MedNet
inclisiranumWHO MedNet
Synonyms  Source
ALN-60212ChemIDplus
ALN-PCSscChemIDplus
ALN-PSCscChEMBL
Brand Name  Source
LeqvioKEGG DRUG
Manual XrefsDatabases
D11931KEGG DRUG
DB14901DrugBank
InclisiranWikipedia
Registry NumbersSources
CAS:1639324-58-5ChemIDplus
Citations