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CHEBI:16827 - corticosterone

ChEBI IDCHEBI:16827
ChEBI Namecorticosterone
Stars
DefinitionA 21-hydroxy steroid that consists of pregn-4-ene substituted by hydroxy groups at positions 11 and 21 and oxo groups at positions 3 and 20. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
Secondary ChEBI IDsCHEBI:3891, CHEBI:14022, CHEBI:19131, CHEBI:41361, CHEBI:57911
Last Modified6 February 2018
DownloadsMolfile
FormulaC21H30O4
Net Charge0
Average Mass346.467
Monoisotopic Mass346.21441
SMILES[H][C@@]12CC[C@]([H])(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@@]21C
InChIInChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChIKeyOMFXVFTZEKFJBZ-HJTSIMOOSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606)
- DOI (10.1038/nbt.2488)
blood serum (BTO:0000133) MetaboLights (MTBLS90)
Mus musculus (ncbitaxon:10090) - PubMed (19425150) Source: BioModels - MODEL1507180067
Roles Classification
Biological Roles:
mouse metabolite  Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
hormone  Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
ChEBI Ontology
Outgoing Relation(s)
corticosterone (CHEBI:16827) has parent hydride pregnane (CHEBI:8386)
corticosterone (CHEBI:16827) has role human metabolite (CHEBI:77746)
corticosterone (CHEBI:16827) has role mouse metabolite (CHEBI:75771)
corticosterone (CHEBI:16827) is a 11β-hydroxy steroid (CHEBI:35346)
corticosterone (CHEBI:16827) is a 20-oxo steroid (CHEBI:36885)
corticosterone (CHEBI:16827) is a 21-hydroxy steroid (CHEBI:35344)
corticosterone (CHEBI:16827) is a 3-oxo-Δ4 steroid (CHEBI:47909)
corticosterone (CHEBI:16827) is a C21-steroid (CHEBI:61313)
corticosterone (CHEBI:16827) is a glucocorticoid (CHEBI:24261)
corticosterone (CHEBI:16827) is a primary α-hydroxy ketone (CHEBI:139590)
Incoming Relation(s)
11-dehydrocorticosterone (CHEBI:78600) has functional parent corticosterone (CHEBI:16827)
11-deoxycorticosterone pivalate (CHEBI:50782) has functional parent corticosterone (CHEBI:16827)
18-hydroxycorticosterone (CHEBI:16485) has functional parent corticosterone (CHEBI:16827)
20β-dihydrocorticosterone (CHEBI:189050) has functional parent corticosterone (CHEBI:16827)
5α-dihydrocorticosterone (CHEBI:180474) has functional parent corticosterone (CHEBI:16827)
5β-dihydrocorticosterone (CHEBI:86381) has functional parent corticosterone (CHEBI:16827)
IUPAC Name 
11β,21-dihydroxypregn-4-ene-3,20-dione
Synonyms  Source
CorticosteroneKEGG COMPOUND
11beta,21-Dihydroxy-4-pregnene-3,20-dioneKEGG COMPOUND
Kendall's compound BKEGG COMPOUND
Reichstein's substance HKEGG COMPOUND
(11β)-11,21-dihydroxypregn-4-ene-3,20-dioneNIST Chemistry WebBook
CORTICOSTERONEPDBeChem
UniProt Name  Source
corticosteroneUniProt
Manual XrefsDatabases
C02140KEGG COMPOUND
C0RPDBeChem
CorticosteroneWikipedia
CORTICOSTERONEMetaCyc
LMST02030186LIPID MAPS
HMDB0001547HMDB
LSM-5814LINCS
Registry NumbersSources
Beilstein:2339601Beilstein
CAS:50-22-6KEGG COMPOUND
CAS:50-22-6ChemIDplus
CAS:50-22-6NIST Chemistry WebBook
Citations