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CHEBI:167658 - CP-724714
| Formula | C27H27N5O3 |
| Net Charge | 0 |
| Average Mass | 469.545 |
| Monoisotopic Mass | 469.21139 |
| SMILES | COCC(=O)NC/C=C/c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1 |
| InChI | InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+ |
| InChIKey | LLVZBTWPGQVVLW-SNAWJCMRSA-N |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1). hepatotoxic agent A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals. |
| Application: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| CP-724714 (CHEBI:167658) has role antineoplastic agent (CHEBI:35610) |
| CP-724714 (CHEBI:167658) has role apoptosis inducer (CHEBI:68495) |
| CP-724714 (CHEBI:167658) has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor (CHEBI:62434) |
| CP-724714 (CHEBI:167658) has role hepatotoxic agent (CHEBI:50908) |
| CP-724714 (CHEBI:167658) is a 2-methoxy-N-[3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide (CHEBI:91331) |
| IUPAC Name |
|---|
| 2-methoxy-N-[(2E)-3-(4-{3-methyl-4-[(6-methylpyridin-3-yl)oxy]anilino}quinazolin-6-yl)prop-2-en-1-yl]acetamide |
| Synonyms | Source |
|---|---|
| 2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide | ChEBI |
| CP724714 | ChEBI |
| CP 724714 | ChemIDplus |
| CP-724,714 | ChemIDplus |
| (E)-2-methoxy-N-[3-[4-[[3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl]amino]quinazolin-6-yl]allyl]ethanamide | ChEBI |
| 2-methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]-acetamide | ChEBI |
| Registry Numbers | Sources |
|---|---|
| CAS:845680-17-3 | ChemIDplus |
| Citations |
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