EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:16480 - nitric oxide
| Formula | NO |
| Net Charge | 0 |
| Average Mass | 30.006 |
| Monoisotopic Mass | 29.99799 |
| SMILES | [N]=O |
| InChI | InChI=1S/NO/c1-2 |
| InChIKey | MWUXSHHQAYIFBG-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Escherichia coli (ncbitaxon:562) | - | PubMed (21988831) | |
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) | |
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Chemical Role: | radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. |
| Biological Roles: | human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). antiviral agent A substance that destroys or inhibits replication of viruses. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. neurotransmitter An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. signalling molecule A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. |
| Applications: | cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. anti-inflammatory agent Any compound that has anti-inflammatory effects. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. renoprotective agent Any compound that is able to prevent damage to the kidneys. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. vasodilator agent A drug used to cause dilation of the blood vessels. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. antifibrotic agent Any agent which acts to reduce fibrosis. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nitric oxide (CHEBI:16480) has role Escherichia coli metabolite (CHEBI:76971) |
| nitric oxide (CHEBI:16480) has role anti-anaemic agent (CHEBI:75835) |
| nitric oxide (CHEBI:16480) has role anti-inflammatory agent (CHEBI:67079) |
| nitric oxide (CHEBI:16480) has role anti-ulcer drug (CHEBI:49201) |
| nitric oxide (CHEBI:16480) has role antifibrotic agent (CHEBI:233423) |
| nitric oxide (CHEBI:16480) has role antifungal agent (CHEBI:35718) |
| nitric oxide (CHEBI:16480) has role antifungal drug (CHEBI:86327) |
| nitric oxide (CHEBI:16480) has role antihypertensive agent (CHEBI:35674) |
| nitric oxide (CHEBI:16480) has role antiinfective agent (CHEBI:35441) |
| nitric oxide (CHEBI:16480) has role antileishmanial agent (CHEBI:70868) |
| nitric oxide (CHEBI:16480) has role antimalarial (CHEBI:38068) |
| nitric oxide (CHEBI:16480) has role antimicrobial agent (CHEBI:33281) |
| nitric oxide (CHEBI:16480) has role antineoplastic agent (CHEBI:35610) |
| nitric oxide (CHEBI:16480) has role antiviral agent (CHEBI:22587) |
| nitric oxide (CHEBI:16480) has role bronchodilator agent (CHEBI:35523) |
| nitric oxide (CHEBI:16480) has role cardiovascular drug (CHEBI:35554) |
| nitric oxide (CHEBI:16480) has role human metabolite (CHEBI:77746) |
| nitric oxide (CHEBI:16480) has role mouse metabolite (CHEBI:75771) |
| nitric oxide (CHEBI:16480) has role neuroprotective agent (CHEBI:63726) |
| nitric oxide (CHEBI:16480) has role neurotransmitter (CHEBI:25512) |
| nitric oxide (CHEBI:16480) has role radical scavenger (CHEBI:48578) |
| nitric oxide (CHEBI:16480) has role renoprotective agent (CHEBI:231911) |
| nitric oxide (CHEBI:16480) has role signalling molecule (CHEBI:62488) |
| nitric oxide (CHEBI:16480) has role vasodilator agent (CHEBI:35620) |
| nitric oxide (CHEBI:16480) is a inorganic radical (CHEBI:36871) |
| nitric oxide (CHEBI:16480) is a nitrogen oxide (CHEBI:35196) |
| nitric oxide (CHEBI:16480) is a reactive nitrogen species (CHEBI:62764) |
| IUPAC Names |
|---|
| oxidonitrogen(•) |
| oxoazanyl |
| Synonyms | Source |
|---|---|
| Amidogen, oxo- | ChEMBL |
| EDRF | ChEBI |
| endothelium-derived relaxing factor | ChEBI |
| Inovent | ChEMBL |
| mononitrogen monoxide | ChemIDplus |
| monóxido de nitrógeno | ChEBI |
| Brand Name | Source |
|---|---|
| Genosyl | ChEMBL |
| UniProt Name | Source |
|---|---|
| nitric oxide | UniProt |
| Registry Numbers | Sources |
|---|---|
| Reaxys:3587257 | Reaxys |
| Gmelin:451 | Gmelin |
| CAS:10102-43-9 | ChemIDplus |
| CAS:10102-43-9 | KEGG COMPOUND |
| CAS:10102-43-9 | NIST Chemistry WebBook |
| Citations |
|---|