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CHEBI:156531 - ficellomycin

ChEBI IDCHEBI:156531
ChEBI Nameficellomycin
Stars
DefinitionA dipeptide antibiotic containing an azabicyclohexane ring system that exhibits potent in vitro activity against Penicillium oxalicum and Staphylococcus aureus. It inhibits semi-conservative DNA replication by causing accumulation of 34S DNA species.
SubmitterMartin Larralde
DownloadsMolfile
FormulaC13H24N6O3
Net Charge0
Average Mass312.374
Monoisotopic Mass312.19099
SMILESCC(C)C(N)C(=O)NC(C(=O)O)C1CC(NC(=N)N)C2CN21
InChIInChI=1S/C13H24N6O3/c1-5(2)9(14)11(20)18-10(12(21)22)7-3-6(17-13(15)16)8-4-19(7)8/h5-10H,3-4,14H2,1-2H3,(H,18,20)(H,21,22)(H4,15,16,17)
InChIKeyDGIHWRUPUISVIZ-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Streptomyces ficellus (ncbitaxon:1977088) - PubMed (28894917) Strain: NRRL8067
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
DNA synthesis inhibitor  Any substance that inhibits the synthesis of DNA.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
ChEBI Ontology
Outgoing Relation(s)
ficellomycin (CHEBI:156531) has part L-valine (CHEBI:16414)
ficellomycin (CHEBI:156531) has part guanidino group (CHEBI:48551)
ficellomycin (CHEBI:156531) has role antibacterial agent (CHEBI:33282)
ficellomycin (CHEBI:156531) has role bacterial metabolite (CHEBI:76969)
ficellomycin (CHEBI:156531) has role DNA synthesis inhibitor (CHEBI:59517)
ficellomycin (CHEBI:156531) is a alkaloid (CHEBI:22315)
ficellomycin (CHEBI:156531) is a aziridines (CHEBI:22681)
ficellomycin (CHEBI:156531) is a dipeptide (CHEBI:46761)
ficellomycin (CHEBI:156531) is a pyrrolidines (CHEBI:38260)
Citations