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CHEBI:156510 - CG-1521

ChEBI IDCHEBI:156510
ChEBI NameCG-1521
Stars
DefinitionAn enamide resulting from the formal condensation of the carboxy group of (2E,4E,6E)-7-phenylhepta-2,4,6-trienoic acid with the amino group of hydroxylamine. It is an inhibitor of histone deacetylase (HDAC) which exhibits anticancer properties.
Last Modified18 September 2020
SubmitterMicheal Alexander
DownloadsMolfile
FormulaC13H13NO2
Net Charge0
Average Mass215.252
Monoisotopic Mass215.09463
SMILESO=C(/C=C/C=C/C=C/c1ccccc1)NO
InChIInChI=1S/C13H13NO2/c15-13(14-16)11-7-2-1-4-8-12-9-5-3-6-10-12/h1-11,16H,(H,14,15)/b2-1+,8-4+,11-7+
InChIKeyDBBYYRWVNDQECM-CDWOPPGASA-N
Roles Classification
Biological Roles:
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 3.5.1.98 (histone deacetylase) inhibitor  An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
CG-1521 (CHEBI:156510) has role antineoplastic agent (CHEBI:35610)
CG-1521 (CHEBI:156510) has role apoptosis inducer (CHEBI:68495)
CG-1521 (CHEBI:156510) has role EC 3.5.1.98 (histone deacetylase) inhibitor (CHEBI:61115)
CG-1521 (CHEBI:156510) is a enamide (CHEBI:51751)
CG-1521 (CHEBI:156510) is a hydroxamic acid (CHEBI:24650)
CG-1521 (CHEBI:156510) is a monocarboxylic acid amide (CHEBI:29347)
IUPAC Name 
(2E,4E,6E)-N-hydroxy-7-phenylhepta-2,4,6-trienamide
Synonyms  Source
CG-1521ChemIDplus
(2E,4E,6E)-N-hydroxy-7-phenyl-2,4,6-heptatrienamideChemIDplus
JW-1521ChEBI
Registry NumbersSources
CAS:674767-29-4ChemIDplus
Citations