EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:156291 - oviedomycin

ChEBI IDCHEBI:156291
ChEBI Nameoviedomycin
Stars
DefinitionA member of the class of tetraphenes that is 1,4,7,12-tetrahydrotetraphene substituted by oxo groups at positions 1, 4, 7, and 12, by hydroxy groups at positions 2, 6 and 8, and by a methyl group at position 3. It is a natural product found in Streptomyces antibioticus ATCC 11891 which exhibits cytotoxicity against A549 human lung cancer cells, HepG2 liver cancer cells, and MCF-7 breast cancer cells.
Last Modified12 August 2020
SubmitterMartin Larralde
DownloadsMolfile
FormulaC19H10O7
Net Charge0
Average Mass350.282
Monoisotopic Mass350.04265
SMILESCc1c(O)c(=O)c2c(cc(O)c3c(=O)c4c(O)cccc4c(=O)c32)c1=O
InChIInChI=1S/C19H10O7/c1-6-15(22)8-5-10(21)13-14(12(8)19(26)16(6)23)17(24)7-3-2-4-9(20)11(7)18(13)25/h2-5,20-21,23H,1H3
InChIKeyLRVJUCBWMNTDLP-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Streptomyces antibioticus (ncbitaxon:1890) - PubMed (15368568) Strain: ATCC 11891
Streptomyces ansochromogenes (ncbitaxon:115647) - PubMed (28972184)
Roles Classification
Biological Roles:
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
bacterial metabolite  Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
oviedomycin (CHEBI:156291) has role antineoplastic agent (CHEBI:35610)
oviedomycin (CHEBI:156291) has role bacterial metabolite (CHEBI:76969)
oviedomycin (CHEBI:156291) is a p-quinones (CHEBI:25830)
oviedomycin (CHEBI:156291) is a angucycline antibiotic (CHEBI:70737)
oviedomycin (CHEBI:156291) is a phenols (CHEBI:33853)
oviedomycin (CHEBI:156291) is a tetraphenes (CHEBI:51067)
IUPAC Name 
2,6,8-trihydroxy-3-methyltetraphene-1,4,7,12-tetrone
Synonyms  Source
2,6,8-trihydroxy-3-methyl-benz[a]anthracene-1,4,7,12-tetroneChEBI
2,6,8-trihydroxy-3-methyl-1,4,7,12-tetrahydrotetraphene-1,4,7,12-tetroneChEBI
3-methyl-2,6,8-trihydroxybenzo[a]anthracene-1,4,7,12-tetroneChEBI
Manual XrefsDatabases
CPD-12942MetaCyc
C00046255KNApSAcK
Registry NumbersSources
CAS:439127-45-4KNApSAcK
Citations