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CHEBI:146243 - JWH-133
| ChEBI ID | CHEBI:146243 |
| ChEBI Name | JWH-133 |
| Stars | |
| Definition | A dibenzopyran that is Δ9-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. |
| Last Modified | 3 March 2020 |
| Submitter | Ceri |
| Downloads |
| Formula | C22H32O |
| Net Charge | 0 |
| Average Mass | 312.497 |
| Monoisotopic Mass | 312.24532 |
| SMILES | [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(C(C)(C)CCC)ccc12 |
| InChI | InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1 |
| InChIKey | YSBFLLZNALVODA-RBUKOAKNSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. CB2 receptor agonist A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. apoptosis inhibitor Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. |
| Applications: | anti-inflammatory agent Any compound that has anti-inflammatory effects. opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. vasodilator agent A drug used to cause dilation of the blood vessels. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| JWH-133 (CHEBI:146243) has role analgesic (CHEBI:35480) |
| JWH-133 (CHEBI:146243) has role anti-inflammatory agent (CHEBI:67079) |
| JWH-133 (CHEBI:146243) has role antineoplastic agent (CHEBI:35610) |
| JWH-133 (CHEBI:146243) has role apoptosis inhibitor (CHEBI:68494) |
| JWH-133 (CHEBI:146243) has role CB2 receptor agonist (CHEBI:146246) |
| JWH-133 (CHEBI:146243) has role opioid analgesic (CHEBI:35482) |
| JWH-133 (CHEBI:146243) has role vasodilator agent (CHEBI:35620) |
| JWH-133 (CHEBI:146243) is a benzochromene (CHEBI:38920) |
| JWH-133 (CHEBI:146243) is a dibenzopyran (CHEBI:39203) |
| JWH-133 (CHEBI:146243) is a organic heterotricyclic compound (CHEBI:26979) |
| IUPAC Name |
|---|
| (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene |
| Synonyms | Source |
|---|---|
| 1,1-dimethylbutyl-1-deoxy-Δ9-THC | ChemIDplus |
| (6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran | SUBMITTER |
| (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene | IUPAC |
| JW 133 | ChemIDplus |
| JWH 133 | SUBMITTER |
| JWH133 | ChEBI |
| Manual Xrefs | Databases |
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| JWH-133 | Wikipedia |
| Registry Numbers | Sources |
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| CAS:259869-55-1 | ChemIDplus |
| Citations |
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