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CHEBI:146243 - JWH-133
| ChEBI ID | CHEBI:146243 |
| ChEBI Name | JWH-133 |
| Stars | |
| Definition | A dibenzopyran that is Δ9-tetrahydrocannabinol which is lacking the hydroxy group and in which the pentyl group at position 3 has been replaced by a 1,1-dimethylbutyl group. A potent and highly selective CB2 receptor agonist. |
| Last Modified | 3 March 2020 |
| Submitter | Ceri |
| Downloads |
| Formula | C22H32O |
| Net Charge | 0 |
| Average Mass | 312.497 |
| Monoisotopic Mass | 312.24532 |
| SMILES | [H][C@@]12CC(C)=CC[C@@]1([H])C(C)(C)Oc1cc(C(C)(C)CCC)ccc12 |
| InChI | InChI=1S/C22H32O/c1-7-12-21(3,4)16-9-10-17-18-13-15(2)8-11-19(18)22(5,6)23-20(17)14-16/h8-10,14,18-19H,7,11-13H2,1-6H3/t18-,19+/m0/s1 |
| InChIKey | YSBFLLZNALVODA-RBUKOAKNSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | apoptosis inhibitor Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. CB2 receptor agonist A cannabinoid receptor agonist that binds to and activates type 2 cannabinoid receptors. |
| Applications: | anti-inflammatory agent Any compound that has anti-inflammatory effects. opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. vasodilator agent A drug used to cause dilation of the blood vessels. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| JWH-133 (CHEBI:146243) has role analgesic (CHEBI:35480) |
| JWH-133 (CHEBI:146243) has role anti-inflammatory agent (CHEBI:67079) |
| JWH-133 (CHEBI:146243) has role antineoplastic agent (CHEBI:35610) |
| JWH-133 (CHEBI:146243) has role apoptosis inhibitor (CHEBI:68494) |
| JWH-133 (CHEBI:146243) has role CB2 receptor agonist (CHEBI:146246) |
| JWH-133 (CHEBI:146243) has role opioid analgesic (CHEBI:35482) |
| JWH-133 (CHEBI:146243) has role vasodilator agent (CHEBI:35620) |
| JWH-133 (CHEBI:146243) is a benzochromene (CHEBI:38920) |
| JWH-133 (CHEBI:146243) is a dibenzopyran (CHEBI:39203) |
| JWH-133 (CHEBI:146243) is a organic heterotricyclic compound (CHEBI:26979) |
| IUPAC Name |
|---|
| (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydro-6H-benzo[c]chromene |
| Synonyms | Source |
|---|---|
| 1,1-dimethylbutyl-1-deoxy-Δ9-THC | ChemIDplus |
| (6aR,10aR)-3-(1,1-dimethylbutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran | SUBMITTER |
| (6aR,10aR)-6,6,9-trimethyl-3-(2-methylpentan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene | IUPAC |
| JW 133 | ChemIDplus |
| JWH 133 | SUBMITTER |
| JWH133 | ChEBI |
| Manual Xrefs | Databases |
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| JWH-133 | Wikipedia |
| Registry Numbers | Sources |
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| CAS:259869-55-1 | ChemIDplus |
| Citations |
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