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CHEBI:143527 - (R)-lisofylline

ChEBI IDCHEBI:143527
ChEBI Name(R)-lisofylline
Stars
ASCII Name(R)-lisofylline
DefinitionA 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus.
Last Modified3 May 2019
SubmitterTheOtherDave
DownloadsMolfile
FormulaC13H20N4O3
Net Charge0
Average Mass280.328
Monoisotopic Mass280.15354
SMILESC[C@@H](O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O
InChIInChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m1/s1
InChIKeyNSMXQKNUPPXBRG-SECBINFHSA-N
Wikipedia
Roles Classification
Biological Roles:
immunomodulator  Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
immunomodulator  Biologically active substance whose activity affects or plays a role in the functioning of the immune system.
ChEBI Ontology
Outgoing Relation(s)
(R)-lisofylline (CHEBI:143527) has role anti-inflammatory agent (CHEBI:67079)
(R)-lisofylline (CHEBI:143527) has role immunomodulator (CHEBI:50846)
(R)-lisofylline (CHEBI:143527) is a 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione (CHEBI:143565)
(R)-lisofylline (CHEBI:143527) is enantiomer of (S)-lisofylline (CHEBI:143564)
Incoming Relation(s)
rac-lisofylline (CHEBI:143567) has part (R)-lisofylline (CHEBI:143527)
(S)-lisofylline (CHEBI:143564) is enantiomer of (R)-lisofylline (CHEBI:143527)
IUPAC Name 
1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione
INNs  Source
lisofyllinumWHO MedNet
lisofyllineVSDB
lisofyllineWHO MedNet
lisofilinaWHO MedNet
Synonyms  Source
(−)-lisofyllineChEBI
(R)-LSFChEBI
1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dioneDrugBank
lisophyllineChemIDplus
CT 1501RChemIDplus
CT-1501RChEBI
Brand Name  Source
ProTecKEGG DRUG
Manual XrefsDatabases
DB12406DrugBank
WO2009099582Patent
D04748KEGG DRUG
LisofyllineWikipedia
Registry NumbersSources
CAS:100324-81-0DrugBank
CAS:100324-81-0ChemIDplus
Citations