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CHEBI:143428 - N-demethylmirtazapine
| Formula | C16H17N3 |
| Net Charge | 0 |
| Average Mass | 251.333 |
| Monoisotopic Mass | 251.14225 |
| SMILES | c1ccc2c(c1)Cc1cccnc1N1CCNCC21 |
| InChI | InChI=1S/C16H17N3/c1-2-6-14-12(4-1)10-13-5-3-7-18-16(13)19-9-8-17-11-15(14)19/h1-7,15,17H,8-11H2 |
| InChIKey | FGLAMNFOHWVQOH-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. human xenobiotic metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. histamine antagonist Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. H1-receptor antagonist H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. histamine antagonist Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| N-demethylmirtazapine (CHEBI:143428) has role anxiolytic drug (CHEBI:35474) |
| N-demethylmirtazapine (CHEBI:143428) has role H1-receptor antagonist (CHEBI:37955) |
| N-demethylmirtazapine (CHEBI:143428) has role histamine antagonist (CHEBI:37956) |
| N-demethylmirtazapine (CHEBI:143428) has role human xenobiotic metabolite (CHEBI:76967) |
| N-demethylmirtazapine (CHEBI:143428) has role serotonergic antagonist (CHEBI:48279) |
| N-demethylmirtazapine (CHEBI:143428) has role α-adrenergic antagonist (CHEBI:37890) |
| N-demethylmirtazapine (CHEBI:143428) is a benzazepine (CHEBI:35676) |
| N-demethylmirtazapine (CHEBI:143428) is a tetracyclic antidepressant (CHEBI:50940) |
| IUPAC Name |
|---|
| 1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Synonyms | Source |
|---|---|
| N-demethylmirtazapine | ChemIDplus |
| N-desmethylmirtazapine | ChemIDplus |
| desmethylmirtazapine | ChemIDplus |
| ORG-3838 | ChemIDplus |
| desmethyl mirtazapine | ChemIDplus |
| demethylmirtazapine | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| HMDB0060956 | HMDB |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3976057 | Beilstein |
| CAS:61337-68-6 | ChemIDplus |
| CAS:61337-68-6 | NIST Chemistry WebBook |
| Citations |
|---|