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CHEBI:143342 - 3-Hydroxyprazepam

ChEBI IDCHEBI:143342
ChEBI Name3-Hydroxyprazepam
Stars
Submittermwilliams
DownloadsMolfile
FormulaC19H17ClN2O2
Net Charge0
Average Mass340.810
Monoisotopic Mass340.09786
SMILESO=C1[C@H](O)N=C(c2ccccc2)c2cc(Cl)ccc2N1CC1CC1
InChIInChI=1S/C19H17ClN2O2/c20-14-8-9-16-15(10-14)17(13-4-2-1-3-5-13)21-18(23)19(24)22(16)11-12-6-7-12/h1-5,8-10,12,18,23H,6-7,11H2/t18-/m0/s1
InChIKeySYUMLTUHTWFDGE-SFHVURJKSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
3-Hydroxyprazepam (CHEBI:143342) is a benzodiazepine (CHEBI:22720)