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CHEBI:143107 - 2-acetamidophenol

Default Structure
ChEBI IDCHEBI:143107
ChEBI Name2-acetamidophenol
Stars
DefinitionA member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties.
Last Modified21 May 2019
SubmitterAnne Morgat
DownloadsMolfile
FormulaC8H9NO2
Net Charge0
Average Mass151.165
Monoisotopic Mass151.06333
SMILESCC(=O)Nc1ccccc1O
InChIInChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10)
InChIKeyADVGKWPZRIDURE-UHFFFAOYSA-N
Roles Classification
Biological Roles:
xenobiotic metabolite  Any metabolite produced by metabolism of a xenobiotic compound.
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Applications:
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
antirheumatic drug  A drug used to treat rheumatoid arthritis.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
ChEBI Ontology
Outgoing Relation(s)
2-acetamidophenol (CHEBI:143107) has role anti-inflammatory agent (CHEBI:67079)
2-acetamidophenol (CHEBI:143107) has role antineoplastic agent (CHEBI:35610)
2-acetamidophenol (CHEBI:143107) has role antirheumatic drug (CHEBI:35842)
2-acetamidophenol (CHEBI:143107) has role apoptosis inducer (CHEBI:68495)
2-acetamidophenol (CHEBI:143107) has role platelet aggregation inhibitor (CHEBI:50427)
2-acetamidophenol (CHEBI:143107) has role xenobiotic metabolite (CHEBI:76206)
2-acetamidophenol (CHEBI:143107) is a acetamides (CHEBI:22160)
2-acetamidophenol (CHEBI:143107) is a phenols (CHEBI:33853)
IUPAC Name 
N-(2-hydroxyphenyl)acetamide
Synonyms  Source
2-acetaminophenolChemIDplus
2-(acetylamino)phenolChEBI
2-(N-acetylamino)phenolChEBI
2-hydroxyacetanilideHMDB
2'-hydroxyacetanilideChemIDplus
acet-o-aminofenolChemIDplus
UniProt Name  Source
2-acetamidophenolUniProt
Manual XrefsDatabases
5Q1JPDB
9KSPDBeChem
HMDB0061919HMDB
US2005049229Patent
Registry NumbersSources
Reaxys:607592Reaxys
CAS:614-80-2NIST Chemistry WebBook
CAS:614-80-2ChemIDplus
Citations