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CHEBI:142623 - spiroiminodihydantoin

ChEBI IDCHEBI:142623
ChEBI Namespiroiminodihydantoin
Stars
DefinitionAn azaspiro compound that is 1,3,6,8-tetraazaspiro[4.4]non-6-ene which is substituted by oxo groups at positions 2, 4, and 9. Both enantiomers are highly mutagenic products resulting from the oxidation of guanine and 8-oxo-7,8-dihydroguanine in DNA by reactive oxygen species.
Last Modified21 January 2019
SubmitterMarija
DownloadsMolfile
FormulaC5H5N5O3
Net Charge0
Average Mass183.127
Monoisotopic Mass183.03924
SMILESNC1=NC2(NC(=O)NC2=O)C(=O)N1
InChIInChI=1S/C5H5N5O3/c6-3-7-1(11)5(9-3)2(12)8-4(13)10-5/h(H3,6,7,9,11)(H2,8,10,12,13)
InChIKeyHJWQNCPSKFANJK-UHFFFAOYSA-N
Roles Classification
Biological Role:
mutagen  An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
ChEBI Ontology
Outgoing Relation(s)
spiroiminodihydantoin (CHEBI:142623) has functional parent hydantoin (CHEBI:27612)
spiroiminodihydantoin (CHEBI:142623) has role mutagen (CHEBI:25435)
spiroiminodihydantoin (CHEBI:142623) is a azaspiro compound (CHEBI:35624)
IUPAC Name 
7-amino-1,3,6,8-tetraazaspiro[4.4]non-6-ene-2,4,9-trione
Citations