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CHEBI:141616 - hapalindole-type alkaloid
| ChEBI ID | CHEBI:141616 |
| ChEBI Name | hapalindole-type alkaloid |
| Stars | |
| Definition | Any member of a structurally diverse group of hybrid isoprenoid-indole alkaloids, produced solely by members of the Subsection V cyanobacterial strains. The major classes of hapalindole-type molecules include hapalindoles, fischerindoles, welwitindolinones and ambiguines that share a common molecular feature where an indole and an isonitrile group are connected by a carbon-carbon motif (C10-C11) that is appended with a monoterpene unit. Fusion of the exomethylene carbon C-16 with indole backbones in the tricyclic hapalindoles provides tetracyclic hapalindoles and fischerindoles that, on rearrangement, can also lead to the bridged tetracyclic welwitindolinones. Decoration of tetracyclic hapalindoles with a tert-prenyl group at C-2 of the indole ring results in ambiguines, of which many have a fused pentacyclic 6-6-6-5-7 or 6-6-6-5-6 ring system. |
| Last Modified | 15 August 2018 |
| Submitter | Gareth Owen |
| Roles Classification |
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| Biological Role: | metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| hapalindole-type alkaloid (CHEBI:141616) is a indole alkaloid (CHEBI:38958) |
| Incoming Relation(s) |
| ambiguine (CHEBI:141618) is a hapalindole-type alkaloid (CHEBI:141616) |
| fischerindole alkaloid (CHEBI:141619) is a hapalindole-type alkaloid (CHEBI:141616) |
| hapalindole (CHEBI:141617) is a hapalindole-type alkaloid (CHEBI:141616) |
| Synonym | Source |
|---|---|
| hapalindole-type alkaloids | ChEBI |
| Citations |
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