forasartan (CHEBI:141552)

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CHEBI:141552 - forasartan

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ChEBI ID	CHEBI:141552
ChEBI Name	forasartan
Stars
Definition	A member of the class of pyridines that is pyridine which is substituted at positions 2 and 5 by o-(tetrazol-5-yl)phenyl and (3,5-dibutyl-1,2,4-triazol-1-yl)methyl groups, respectively. It is a nonpeptide antagonist of angiotensin II, type 1 (AT₁) receptors, used for the treatment of hypertension.
Last Modified	20 September 2018
Submitter	Bijay
Downloads	Molfile

Formula	C23H28N8
Net Charge	0
Average Mass	416.533
Monoisotopic Mass	416.24369
SMILES	CCCCc1nc(CCCC)n(Cc2ccc(-c3ccccc3-c3nnnn3)nc2)n1
InChI	InChI=1S/C23H28N8/c1-3-5-11-21-25-22(12-6-4-2)31(28-21)16-17-13-14-20(24-15-17)18-9-7-8-10-19(18)23-26-29-30-27-23/h7-10,13-15H,3-6,11-12,16H2,1-2H3,(H,26,27,29,30)
InChIKey	YONOBYIBNBCDSJ-UHFFFAOYSA-N

Wikipedia

Roles Classification

Biological Role:	angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors.
Applications:	angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.

ChEBI Ontology

Outgoing Relation(s)
	forasartan (CHEBI:141552) has role angiotensin receptor antagonist (CHEBI:61016)
	forasartan (CHEBI:141552) has role antihypertensive agent (CHEBI:35674)
	forasartan (CHEBI:141552) is a benzenes (CHEBI:22712)
	forasartan (CHEBI:141552) is a pyridines (CHEBI:26421)
	forasartan (CHEBI:141552) is a tetrazoles (CHEBI:35689)
	forasartan (CHEBI:141552) is a triazoles (CHEBI:35727)

IUPAC Name
5-[(3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(1H-tetrazol-5-yl)phenyl]pyridine

INNs	Source
forasartan	ChemIDplus
forasartanum	WHO MedNet
forasartan	WHO MedNet
forasartán	WHO MedNet

Synonyms	Source
SC-52458	SUBMITTER
SC 52458	ChemIDplus

Manual Xrefs	Databases
Forasartan	Wikipedia
D04243	KEGG DRUG
HMDB0015434	HMDB
DB01342	DrugBank

Registry Numbers	Sources
Reaxys:9361619	Reaxys
CAS:145216-43-9	ChemIDplus

Citations