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CHEBI:141336 - α-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-β-D-GlcNAc-(1→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-NeuAc-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer

ChEBI IDCHEBI:141336
ChEBI Nameα-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-β-D-GlcNAc-(1→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-NeuAc-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer
Stars
ASCII Namealpha-L-Fuc-(1->3)-[beta-D-Gal-(1->4)]-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-NeuAc-(2->3)]-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-Cer
DefinitionA sialoheptaosylceramide consisting of the branched octasaccharide α-L-fucosyl-(1→3)-[β-D-galactosyl-(1→4)]-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→3)-N-acetyl-β-D-galactosaminyl-(1→4)-[N-acetyl-α-neuraminyl-(2→3)]-β-D-galactosyl-(1→4)-β-D-glucose attached to the primary hydroxy function of a ceramide with an undefined sphingoid base. It represents a hybrid structure of type 2 Lex epitope and GM1 ganglioside core structure, designated as Lex-GM1.
Last Modified13 July 2018
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC61H100N4O45R1R2
Net Charge0
Average Mass (excl. R groups)1609.449
Monoisotopic Mass (excl. R groups)1608.56596
SMILES[1*]C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@H](O)[C@H](O[C@@H]5O[C@H](CO)[C@@H](O[C@@H]6O[C@H](CO)[C@H](O)[C@H](O)[C@H]6O)[C@H](O[C@@H]6O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]6O)[C@H]5NC(C)=O)[C@H]4O)[C@H]3NC(C)=O)[C@H](O[C@]3(C(=O)O)C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O3)[C@H]2O)[C@H](O)[C@H]1O)[C@@H]([2*])O
Roles Classification
Biological Role:
antigen  Any substance that stimulates an immune response in the body, such as through antibody production or by presentation to a T-cell receptor after binding to a major histocompability complex (MHC).
ChEBI Ontology
Outgoing Relation(s)
α-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-β-D-GlcNAc-(1→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-NeuAc-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer (CHEBI:141336) has role antigen (CHEBI:59132)
α-L-Fuc-(1→3)-[β-D-Gal-(1→4)]-β-D-GlcNAc-(1→3)-β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-NeuAc-(2→3)]-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-Cer (CHEBI:141336) is a sialoheptaosylceramide (CHEBI:60914)
IUPAC Name 
5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranonosyl-(2→3)-[6-deoxy-α-L-galactopyranosyl-(1→3)-[β-D-galactopyranosyl-(1→4)]-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1→4)]-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside
Synonyms  Source
Lex-GM1ChEBI
188C1 gangliosideChEBI
α-L-Fucp-(1→3)-[β-D-Galp-(1→4)]-β-D-GlcpNAc-(1→3)-β-D-Galp-(1→3)-β-D-GalpNAc-(1→4)-[α-NeupAc-(2→3)]-β-D-Galp-(1→4)-β-D-Glcp-(1↔1')-CerChEBI
Citations