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CHEBI:140624 - disialosyl Gb5(2−)
| Formula | C58H92N4O44R2 |
| Net Charge | -2 |
| Average Mass (excl. R groups) | 1549.354 |
| Monoisotopic Mass (excl. R groups) | 1548.50844 |
| SMILES | [1*]C(=O)N[C@@H](CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O[C@H]3O[C@H](CO)[C@H](O)[C@H](O[C@@H]4O[C@H](CO[C@]5(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O5)[C@H](O)[C@H](O[C@@H]5O[C@H](CO)[C@H](O)[C@H](O[C@]6(C(=O)[O-])C[C@H](O)[C@@H](NC(C)=O)[C@]([H])([C@H](O)[C@H](O)CO)O6)[C@H]5O)[C@H]4NC(C)=O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@@H]([2*])O |
| Roles Classification |
|---|
| Biological Role: | tumour antigen An antigenic substance produced in tumour cells, which triggers an immune response in the host. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| disialosyl Gb5(2−) (CHEBI:140624) has functional parent Monosialyl-Gb5(1−) (CHEBI:140623) |
| disialosyl Gb5(2−) (CHEBI:140624) has role tumour antigen (CHEBI:144829) |
| disialosyl Gb5(2−) (CHEBI:140624) is a globoside (CHEBI:61360) |
| disialosyl Gb5(2−) (CHEBI:140624) is a glycoheptaosylceramide (CHEBI:36640) |
| Incoming Relation(s) |
| α-NeuAc-(2→3)-β-D-Gal-(1→3)-[α-NeuAc-(2→6)]-β-D-GalNAc-(1→3)-α-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-N-acylsphinganine (CHEBI:140719) is a disialosyl Gb5(2−) (CHEBI:140624) |
| α-NeuAc-(2→3)-β-D-Gal-(1→3)-[α-NeuAc-(2→6)]-β-D-GalNAc-(1→3)-α-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-N-acylsphingosine (CHEBI:140721) is a disialosyl Gb5(2−) (CHEBI:140624) |
| α-NeuAc-(2→3)-β-D-Gal-(1→3)-[α-NeuAc-(2→6)]-β-D-GalNAc-(1→3)-α-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Glc-(1↔1')-ceramide(t18:0) (CHEBI:141012) is a disialosyl Gb5(2−) (CHEBI:140624) |
| IUPAC Name |
|---|
| 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranonosyl-(2→6)-[5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranonosyl-(2→3)-β-D-galactopyranosyl-(1→3)]-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1→3)-α-D-galactopyranosyl-(1→4)-β-D-galactopyranosyl-(1→4)-β-D-glucopyranose-(1↔1')-ceramide |
| Synonyms | Source |
|---|---|
| V3NeuAcIV6NeuAc-Gb5Cer(2−) | SUBMITTER |
| DSGG(2−) | SUBMITTER |
| DSGG globoside | ChEBI |
| α-Neup5Ac-(2→3)-β-D-Galp-(1→3)-[α-Neup5Ac-(2→6)]-β-D-GalpNAc-(1→3)-α-D-Galp-(1→4)-β-D-Galp-(1→4)-β-D-Glcp-(1→1')-Cer | ChEBI |
| N-acetyl-α-neuraminyl-(2→3)-β-D-galactosyl-(1→3)-[N-acetyl-α-neuraminyl-(2→6)]-N-acetyl-β-D-galactosaminyl-(1→3)-α-D-galactosyl-(1→4)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1')-ceramide | ChEBI |
| UniProt Name | Source |
|---|---|
| a globoside DSGG | UniProt |
| Manual Xrefs | Databases |
|---|---|
| G00181 | KEGG GLYCAN |
| HMDB0006588 | HMDB |
| Citations |
|---|