EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:140273 - 7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid

Default Structure
ChEBI IDCHEBI:140273
ChEBI Name7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid
Stars
ASCII Name7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid
DefinitionA dihydroxydocosapentaenoic acid (DiHDPE) that is (8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid carrying two hydroxy substituents at positions 7 and 17. An intermediate of specialized proresolving mediators
Last Modified13 March 2018
SubmitterBijay
DownloadsMolfile
FormulaC22H34O4
Net Charge0
Average Mass362.510
Monoisotopic Mass362.24571
SMILESCC/C=C\CC(O)/C=C/C=CCC=C/C=C\C(O)CCCCCC(=O)O
InChIInChI=1S/C22H34O4/c1-2-3-10-15-20(23)16-11-7-5-4-6-8-12-17-21(24)18-13-9-14-19-22(25)26/h3,5-8,10-12,16-17,20-21,23-24H,2,4,9,13-15,18-19H2,1H3,(H,25,26)/b7-5?,8-6?,10-3-,16-11+,17-12-
InChIKeyJUBMLVBCKBUAQW-RULBWSPQSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - PubMed (23736886)
Roles Classification
Chemical Roles:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
specialised pro-resolving mediator  A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
human xenobiotic metabolite  Any human metabolite produced by metabolism of a xenobiotic compound in humans.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
specialised pro-resolving mediator  A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
ChEBI Ontology
Outgoing Relation(s)
7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid (CHEBI:140273) has role human xenobiotic metabolite (CHEBI:76967)
7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid (CHEBI:140273) has role specialised pro-resolving mediator (CHEBI:140399)
7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid (CHEBI:140273) is a DiHDPE (CHEBI:72656)
7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid (CHEBI:140273) is conjugate acid of 7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoate (CHEBI:140419)
Incoming Relation(s)
7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoate (CHEBI:140419) is conjugate base of 7,17-dihydroxy-(8Z,15E,19Z)-docosa-8,10,13,15,19-pentaenoic acid (CHEBI:140273)
IUPAC Name 
(8Z,15E,19Z)-7,17-dihydroxydocosa-8,10,13,15,19-pentaenoic acid
Synonyms  Source
7,17-dihydroxy-(8Z,10,13,15E,19Z)-docosapentaenoic acidChEBI
7,17-dihydroxy-omega3-docosapentaenoic acidChEBI
7,17-dihydroxy-ω3-docosapentaenoic acidChEBI
resolvin D5n-3 DPAChEBI
RvD5n-3 DPASUBMITTER
Citations