(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265)

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CHEBI:140265 - (10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid

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ChEBI ID	CHEBI:140265
ChEBI Name	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid
Stars
ASCII Name	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid
Definition	A dihydroxydocosapentaenoic acid (DiHDPE) that is (7Z,11E,13E,15Z,19Z)-docosapentaenoic acid in which the hydrogens at the 10 pro-R and 17 pro-S positions have been replaced by hydroxy groups. It is an intermediate of specialized proresolving mediators.
Last Modified	12 March 2018
Submitter	Bijay
Downloads	Molfile

Formula	C22H34O4
Net Charge	0
Average Mass	362.510
Monoisotopic Mass	362.24571
SMILES	CC/C=C\C[C@H](O)/C=C\C=C\C=C\[C@H](O)C/C=C\CCCCCC(=O)O
InChI	InChI=1S/C22H34O4/c1-2-3-10-15-20(23)17-12-8-9-13-18-21(24)16-11-6-4-5-7-14-19-22(25)26/h3,6,8-13,17-18,20-21,23-24H,2,4-5,7,14-16,19H2,1H3,(H,25,26)/b9-8+,10-3-,11-6-,17-12-,18-13+/t20-,21+/m0/s1
InChIKey	QJJOLZOJRISMDP-UENSAESPSA-N

Species of Metabolite	Component	Source	Comments
Homo sapiens (ncbitaxon:9606)	-	PubMed (23736886)

Roles Classification

Chemical Roles:	Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:	specialised pro-resolving mediator A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation. human xenobiotic metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:	specialised pro-resolving mediator A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.

ChEBI Ontology

Outgoing Relation(s)
	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265) has role human xenobiotic metabolite (CHEBI:76967)
	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265) has role specialised pro-resolving mediator (CHEBI:140399)
	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265) is a DiHDPE (CHEBI:72656)
	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265) is a protectin (CHEBI:193572)
	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265) is conjugate acid of (10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoate (CHEBI:140405)
Incoming Relation(s)
Incoming Relation(s)	(10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoate (CHEBI:140405) is conjugate base of (10R,17S)-dihydroxy-(7Z,11E,13E,15Z,19Z)-docosapentaenoic acid (CHEBI:140265)

IUPAC Name
(7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosa-7,11,13,15,19-pentaenoic acid

Synonyms	Source
PD1_{n-3 DPA}	SUBMITTER
(PD)1_{n-3 DPA}	ChEBI
protectin D1_{n-3 DPA}	ChEBI
10(R),17(S)-dihydroxy-omega3-docosapentaenoic acid	ChEBI
10(R),17(S)-dihydroxy-ω3-docosapentaenoic acid	ChEBI
(7Z,10R,11E,13E,15Z,17S,19Z)-10,17-dihydroxydocosapentaenoic acid	ChEBI

Registry Numbers	Sources
Reaxys:27066730	Reaxys

Citations